17-ketosteroid fractionation

Primary hypogonadism (indicating an intrinsic problem with the testes in males) leads to decreased testosterone synthesis and increased conversion of testosterone to estradiol potentially leading to a gynecomastic appearance. [13] Klinefelter syndrome is a notable example of a disorder that causes hypogonadism, gynecomastia, and has a higher risk of breast cancer in males (20–50 times higher than males without the disorder). [33] Central hypogonadism (indicating a problem with the brain) leads to decreased production and release of luteinizing hormone (LH) (a stimulatory signal for endogenous steroid hormone synthesis) which leads to decreased production of testosterone and estradiol in the testes. [13]

17-ketosteroid fractionation

17-ketosteroid fractionation

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17-ketosteroid fractionation17-ketosteroid fractionation17-ketosteroid fractionation17-ketosteroid fractionation17-ketosteroid fractionation

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