Metabolic pathway databases may draw on enzyme, compound and gene databases, but usually go beyond them to show how enzyme reactions link to one another and ultimately form pathways for catabolism, anabolism or other necessary cellular functions. Public metabolic databases may contain information on pathways shared by many organisms; these may omit specialized metabolism. Others may limit themselves to share or unique pathways found in specific organisms, or specialized metabolism. Metabolic pathway databases are a resource for metabolic engineering. Genetic material from microbes, plants and animals is being modified at the present time; these modifications are often based on information mined from a pathway database. Mining of metabolic data is still in its infancy. Based on information stored in today's metabolic databases, it may be possible in the future to predict metabolic pathways for the biodegradation of novel environmental toxins or biosynthesis of needed specialty chemicals.
Side-effects from the use of steroids are extremely common and can be quite significant. Most side-effects are reversible once the athlete stops usage although serious long-term side-effects and even death have occurred as a direct result of steroid use.
• Decreased sperm production and sex drive
• Increased aggression, irritability and mood swings
• Liver disorders
• Baldness (alopecia)
• Hypertension (high blood pressure)
• Raised cholesterol
• Gynecomastia (development of over-sized mammary glands in males)
• Menstrual irregularities (in women)
• Hirsuitism (excessive hair growth occurring in females which follows the pattern of male hair growth, . facial)
• Deepening of the voice
• Reduced immunity
• Possible development of tumors (wilm’s tumor, prostate carcinoma and leukemia have been reported, although a connection is not proven)