Buffalo hump steroid use



Follow up
In general, the first postoperative follow-up visit will be scheduled a few weeks after surgery. If problems develop prior to your appointment, you will be asked to return to your neurosurgeon as soon as possible. Your return appointments will be scheduled according to your needs. Lifelong follow-up is necessary. You should ensure that you receive appropriate follow-up by physicians knowledgeable in diagnosing and managing pituitary disorders.

Medical Therapy
For patients who continue to have excess pituitary production of ACTH following surgery, medications can be helpful along with other therapies. Although there is no medication to control Cushing’s disease, a few drugs can be used in reducing the levels of cortisol. Drugs such as ketoconazole, metyrapone, and mitotane, trilostane, and aminoglutethimide have been used with varying success. These drugs may be given after surgery (sometimes along with radiation treatments).

The symptoms, disabilities and life-style of a person with Cushing’s Syndrome depend on the degree of cortisol excess, the duration of the disease, the basic health of the person, but especially the type and curability of the Cushing’s Syndrome. If it is cured, all of the features of the disease can resolve, but this may take as long as 2 to 18 months. During that time, most people get annoyed and frustrated by the slow improvements in physical changes and the combination of Cushing’s and adrenal insufficiency signs and symptoms (dizziness, weakness, nausea, loss of appetite) as replacement steroid hormones are tapered and adrenal hormone production slowly improves toward normal. Frequent calls and visits to physicians are necessary.

amnesia , anxiety, benign intracranial hypertension , convulsions, delirium , dementia (characterized by deficits in memory retention, attention, concentration, mental speed and efficiency, and occupational performance), depression, dizziness, EEG abnormalities, emotional instability and irritability, euphoria , hallucinations, headache, impaired cognition , incidence of severe psychiatric symptoms, increased intracranial pressure with papilledema ( pseudotumor cerebri ) usually following discontinuation of treatment, increased motor activity, insomnia, ischemic neuropathy , long-term memory loss, mania , mood swings, neuritis, neuropathy, paresthesia , personality changes, psychiatric disorders including steroid psychoses or aggravation of pre-existing psychiatric conditions, restlessness, schizophrenia , verbal memory loss, vertigo , withdrawn behavior.

Steroids killed nine-year-old Lexie McConnell after only five and a half weeks. In August 1993, Lexie was diagnosed as having toxoplasmosis. The consultant put her on 80 mg per day of prednisolone. Immediately, she suffered severe side effects, huge weight gain , terrible pains, holes in her tongue and black stools. After nearly a month, at her parents' pleading, the doctors quickly lowered the dosage to 60 mg, 40 mg, 20 mg. In excruciating pain, Lexie was taken to a hospital, where it was discovered she'd contracted chickenpox. Four days later, she died. A few years later, another eye specialist declared that a simple course of antibiotics could have cleared up her infection. The above excerpt is from Ursula Kelly's site

The use of steriods has not been mentioned again by the NP or the doc on my 3-4 follow up visits trying to determine what has caused this and why it is causing pain.  What they have done is a c-spine, chest x-ray, CT scan.  CT scan results suggested fatty tissue may be result of steriod use and/or Cushings Disease.  So they then tested my cortisol level for Cushings...negative BUT now they want me back in to test my hormone level for polysystic ovarian disease.  Based upon what I've read about that...I have absolutely none of the symptoms. 

Buffalo hump steroid use

buffalo hump steroid use

Steroids killed nine-year-old Lexie McConnell after only five and a half weeks. In August 1993, Lexie was diagnosed as having toxoplasmosis. The consultant put her on 80 mg per day of prednisolone. Immediately, she suffered severe side effects, huge weight gain , terrible pains, holes in her tongue and black stools. After nearly a month, at her parents' pleading, the doctors quickly lowered the dosage to 60 mg, 40 mg, 20 mg. In excruciating pain, Lexie was taken to a hospital, where it was discovered she'd contracted chickenpox. Four days later, she died. A few years later, another eye specialist declared that a simple course of antibiotics could have cleared up her infection. The above excerpt is from Ursula Kelly's site

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