I have PCOS, and have been on Metformin for about 16 years now. I had very few periods as a young woman (about once a year) and low fertility, and treated with hormones to get pregnant in my early 30’s. (Got twins!). Yet, it took my sister who is a gynecologist to point out that I probably had PCOS, and sure enough. That’s when I went on Metformin for my heart health. About two years ago I started taking green coffee bean extract. It worked so well that I could cut my Metformin dose in half. When I excitedly told my endocrinologist about it she was completely uninterested in my comments about the green coffee bean extract, and thought instead it was all diet related. I tried to tell her that my diet had not changed, but she would not listen. I just found out about N-acetylcysteine and am eager to try that as well. Be well, all of you. There are ways to get better, and sometimes we have to do research on our own to find some answers… And thank you to the researcher who try to help!
Approximate mean ages for the onset of various pubertal changes are as follows. Ages in parentheses are the approximate 3rd and 97th percentiles for attainment. For example, less than 3% of girls have not yet achieved thelarche by 13 years of age. Developmental changes during puberty in girls occur over a period of 3 – 5 years, usually between 10 and 15 years of age. They include the occurrence of secondary characteristics beginning with breast development, the adolescent growth spurt, the onset of menarche – which does not correspond to the end of puberty – and the acquisition of fertility , as well as profound psychological modifications.
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