Steroid hormone precursors

FIGURE 2. Major Pathways of Steroid Biosynthesis.
The pathways outlined here are common to the adrenals, the gonads and, to some extent, to the fetoplacental unit. The first committed step is the conversion of cholesterol to pregnenolone, catalysed by the P-450scc enzyme, which is under pituitary hormone control (ACTH or LH depending on the tissue). Cholesterol side-chain removal is blocked specifically by aminoglutethimide , a steroid biosynthesis inhibitor. From pregnenolone, steroid biosynthesis can proceed either through the so-called "delta-5" pathway (17α-hydroxypregnenolone, dehydroepiandrosterone, testosterone), or through the "delta-4" pathway (progesterone onwards). Progesterone is the starting point for mineralocorticoid synthesis, whereas glucocorticoids are derived from its metabolite, 17α-hydroxyprogesterone. Estrogens are formed from androgens (androstenedione and/or testosterone). Most reactions are irreversible (as denoted by a single arrow). Reversible reactions (double arrows) depend on cofactor availability (. the NADP/NADPH ratio). [Abbreviations used here for the various enzymes are listed in the figure].

There are no tell, tell signs of steroid abuse like there are with recreational drugs and this can make true abuse a little difficult to spot. However, here at we want to look at all aspects of steroid use, and in doing so, give you a better understanding of the topic at hand. Some of what you find will be nothing new, but much of it promises to be information that you’ve never been told. There is so much to discuss when it comes to this topic, and we guarantee when it comes to steroid abuse you may very well find what you once believed will rapidly change once exposed to the truth.

Prednisone is a drug that belongs to the corticosteroid drug class, and is an anti-inflammatory and immune system suppressant. It's used to treat a variety of diseases and conditions, for example: inflammatory bowel disease (Crohn's disease and ulcerative colitis), lupus, asthma, cancers, and several types of arthritis.

Common side effects are weight gain, headache, fluid retention, and muscle weakness. Other effects and adverse events include glaucoma, cataracts, obesity, facial hair growth, moon face, and growth retardation in children. This medicine also causes psychiatric problems, for example: depression, insomnia, mood swings, personality changes, and psychotic behavior. Serious side effects include reactions to diabetes drugs, infections, and necrosis of the hips and joints.

Corticosteroids like prednisone, have many drug interactions; examples include: estrogens, phenytoin (Dilantin), diuretics, warfarin (Coumadin, Jantoven), and diabetes drugs. Prednisone is available as tablets of 1, , 10, 20, and 50 mg; extended release tablets of 1, 2, and 5mg; and oral solution of 5mg/5ml. It's use during the first trimester of pregnancy may cause cleft palate. This medicine is secreted in breast milk and can cause side effects in infants who are nursing. You should not stop taking prednisone abruptly because it can cause withdrawal symptoms and adrenal failure. Talk with your doctor, pharmacist, or other medical professional if you have questions about beta-blockers. Talk with your doctor, pharmacist, or other medical professional if you have questions about prednisone.

If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

We are always on top of the latest news regarding steroids. Whether it`s steroids in sports like baseball, football, bodybuilding, boxing, or the olympics-we cover it! Our news blog is updated daily with fresh content that involves steroid use around the world. is a great resource for learning about a variety of topics regarding performance enhancing drugs like dianabol, anadrol, deca-durabolin, winstrol-v, and sustanon.

Our website provides information about anabolic steroids strictly for educational reasons only. If you are interested in learning about the latest headlines involving the use of steroids and HGH (human growth hormone) , than you have come to the right place. It`s important to always consult your physician before taking any drugs and that includes legal steroids. Please understand and make clear that does not approve or condone illegal use of anabolic steroids without a doctors prescription. Be sure to understand the laws in the country you reside when you plan to buy steroids . will not be responsible for anyone who has misused an anabolic steroid, or other legal steroids described on this website. Must be 18 years old to visit and view the contents of

Please consult with your physician before you buy steroids or buy anabolic steroids .

Steroid hormone precursors

steroid hormone precursors

We are always on top of the latest news regarding steroids. Whether it`s steroids in sports like baseball, football, bodybuilding, boxing, or the olympics-we cover it! Our news blog is updated daily with fresh content that involves steroid use around the world. is a great resource for learning about a variety of topics regarding performance enhancing drugs like dianabol, anadrol, deca-durabolin, winstrol-v, and sustanon.

Our website provides information about anabolic steroids strictly for educational reasons only. If you are interested in learning about the latest headlines involving the use of steroids and HGH (human growth hormone) , than you have come to the right place. It`s important to always consult your physician before taking any drugs and that includes legal steroids. Please understand and make clear that does not approve or condone illegal use of anabolic steroids without a doctors prescription. Be sure to understand the laws in the country you reside when you plan to buy steroids . will not be responsible for anyone who has misused an anabolic steroid, or other legal steroids described on this website. Must be 18 years old to visit and view the contents of

Please consult with your physician before you buy steroids or buy anabolic steroids .

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